Discover the power of Traction Force Microscopy (TFM), a cutting-edge technique that quantifies the forces exerted by cells on their surrounding substrate. TFM provides valuable insights into cell mechanics, migration, and interactions with the extracellular matrix, unlocking a deeper understanding of cellular behavior. In our research, we harness the potential of TFM with soft pillars, a specialized variation of this technique known as elastic micropost arrays or micropillar substrates. By leveraging TFM with soft pillars, we delve into the fascinating field of mechanobiology of cancer cells, unraveling the intricate dynamics of cell-substrate interactions.

We are working on developing cellulose-based sensors and mini-organs using a fabrication technique that involves Parylene C/O2 plasma treatment. The amount of Parylene C coating is controlled to study its effect on membrane porosity, with comparisons of hydrophilic pattern resolution to showcase the advantages of porosity control. Moreover, this treatment enhances the elasticity of porous membranes, enabling the construction of biosensors and actuating organs, such as lungs.